BDBM50233538 18beta-glycyrrhetic acid::3beta-hydroxy-11-oxoolean-12-en-30-oic acid::CHEMBL230006::US11660306, Example 18beta Glycyrrhetinic acid::glycyrrhetinic acid
SMILES CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O
InChI Key InChIKey=MPDGHEJMBKOTSU-YKLVYJNSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50233538
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 11beta-HSD2 overexpressed in microsomal fraction of HEK293 cells using [3H]-cortisol as substrate by scintillation proximity assa...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Vienna University Of Technology
Curated by ChEMBL
Vienna University Of Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of rat renal 11beta-HSD2 in rat liver assessed as inhibition of cortisone productionMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Vienna University Of Technology
Curated by ChEMBL
Vienna University Of Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of rat renal 11beta-HSD2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair